Research objective: HTA promotes 3 principles: Systematic literature search, analysis and appraisal, transparent presentation of the HTA process and methods, interdisciplinary perspective. New medical interventions in particular are often explosive since different interest groups - naturally - assess them differently in terms of innovation/medical advance and "stage of maturity" (still experimental or qualified for broader diffusion). The intention of the internal manual is the standardization of processes and of terminology, and of supporting research with toolkits such as templates for the external and internal validity of studies, evidence tables, classification schemes etc. A special focus on methodological questions concerning rapid assessments of new/innovative technologies.