LBI-HTA - Publications - Search - Meniscal allograft transplantation for post-meniscectomy syndrome

Vreugdenburg, T. and Fischer, S. (2018): Meniscal allograft transplantation for post-meniscectomy syndrome. Decision Support Document 112.

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Abstract

Post-meniscectomy syndrome is broadly characterised by intractable pain following the partial or total removal of a meniscus. An new treatment approach is meniscal allograft transplantation (MAT), which involves the transplant of a cadaveric meniscal allograft into the knee of a patient who has had a prior (sub)total meniscectomy. The aim of our report was to evaluate the efficacy and safety of MAT for the treatment of post-meniscectomy syndrome, compared to conservative treatment.

Overall, the level of evidence was very low. We could only identify one controlled trial, which showed superiority of MAT in some (but not all) outcomes compared to conservative treatment. In addition, we identified five case series to evaluate the safety. The complications rate in these case series was 0-38.5%.

The inclusion of MAT in the hospital benefit catalogue is therefore not recommended.

Item Type:Decision Support Document
Keywords:Post-meniscectomy syndrome, knee pain, meniscal allograft transplantation, conservative treatment
Subjects:WB Practice of medicine > WB 300-962 Therapeutics
W Health professions > W 100-275 Medical, dental and pharmaceutical service plans
WO Surgery > WO 500-517 Operative surgical procedures. Techniques
WE Musculoskeletal system > WE 300-400 Joint tissues
WE Musculoskeletal system > WE 168-190 Orthopedics
WO Surgery > WO 660-690 Transplantation
WE Musculoskeletal system > WE 800-890 Extremities and podiatry
Language:English
Series Name:Decision Support Document 112
Deposited on:20 Jul 2018 11:44
Last Modified:20 Jul 2018 11:44

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