LBI-HTA - Publications - Search - (Percutaneous) left atrial appendage closure for the prevention of thromboembolic events in patients with atrial fibrillation. 3rd Update 2018

Semlitsch, T. and Krenn, C. (2018): (Percutaneous) left atrial appendage closure for the prevention of thromboembolic events in patients with atrial fibrillation. 3rd Update 2018. Decision Support Document 44/ Update 2018.

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Abstract

This report is the third update of a systematic review compiled in 2011 and evaluates the efficacy and safety of left atrial appendage closure (LAAC) either using percutaneous LAAC devices or a surgically implanted special clip compared to oral anticoagulation (OAC) for stroke prevention in patients with atrial fibrillation.

The currently available evidence is not sufficient to prove that the percutaneous LAAC is as effective and as safe as OAC. Especially comparative studies on non-vitamin K oral anticoagulants (NOACs) are missing. For LAAC with the surgically implanted special clip, there is no evidence that allows an evaluation of efficacy and safety.

At present, the inclusion into the Austrian hospital benefit catalogue is not recommended for both interventions. A re-evaluation is proposed in 2023.

Item Type:Decision Support Document
Keywords:Left atrial appendage, oral anticoagulation, atrial fibrillation, thromboembolism, stroke
Subjects:WB Practice of medicine > WB 300-962 Therapeutics
WO Surgery > WO 500-517 Operative surgical procedures. Techniques
W Health professions > W 100-275 Medical, dental and pharmaceutical service plans
WG Cardiovascular system
Language:German
Series Name:Decision Support Document 44/ Update 2018
Deposited on:20 Jul 2018 11:52
Last Modified:20 Jul 2018 11:52

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