Rosian, K. and Piso, B. (2017): Radiofrequency ablation for metastatic spinal lesions. Decision Support Document 108.
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Many tumour patients develop painful vertebral metastases in the course of their disease that destroy the vertebrae and often do not adequately respond to standard therapies. We reviewed current evidence on efficacy and safety of radiofrequency ablation (RFA), a minimally invasive procedure, in patients with painful vertebral metastases.
Four prospective and five retrospective single-arm studies were evaluated. Overall, the level of evidence for efficacy is not estimable and "very low" for safety outcomes. The current evidence suggests that RFA leads to a significant pain reduction and an improvement in health-related quality of life. Furthermore, no major complications occurred for the use of RFA. However, the studies have several limitations.
Therefore, we recommend the inclusion of RFA in the Austrian BMGF catalogue of procedures with restrictions and suggest a re-evaluation after 2021.
|Item Type:||Decision Support Document|
|Keywords:||Radiofrequency ablation, vertebral metastases, minimally invasive image-guided procedure|
|Subjects:||WB Practice of medicine > WB 300-962 Therapeutics|
WO Surgery > WO 500-517 Operative surgical procedures. Techniques
W Health professions > W 100-275 Medical, dental and pharmaceutical service plans
WE Musculoskeletal system > WE 720-755 Back
WE Musculoskeletal system > WE 200-259 Bones
WB Practice of medicine > WB 310 Palliative care
WO Surgery > WO 505 Minimally invasive surgical procedures
|Series Name:||Decision Support Document 108|
|Deposited on:||17 Jul 2017 12:07|
|Last Modified:||17 Jul 2017 12:07|
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