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Kisser, A. and Kirisits, A. (2015): Endovascular embolization of unruptured intracranial aneurysms with flow diverters. Decision Support Document 83.

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Abstract

Certain high risk unruptured intracranial aneurysms (IA) are not amenable to preventive treatment by coiling or clipping. We reviewed current evidence on efficacy and safety of a minimally invasive alternative treatment: the endovascular embolisation of the IA using flow diverters.

Five prospective uncontrolled studies were evaluated. There is moderate evidence for efficacy using the angiographic surrogate parameter aneurysm occlusion in a large percentage of treated aneurysms. The current evidence is, however, not sufficient to prove, that the assessed technology of endovascular embolisation with flow diverters is more effective and safe with regards to clinical outcomes than no treatment, endovascular coiling or surgical clipping.

At present, we recommend against the inclusion of flow diverters in the Austrian BMG catalogue of procedures and suggest a re-evaluation in 2017.

Item Type:Decision Support Document
Keywords:Intracranial aneurysm, giant intracranial aneurysm, therapeutic embolisation, flow diverter
Subjects:WB Practice of medicine > WB 300-962 Therapeutics
WA Public health > WA 108-245 Preventive medicine
WO Surgery > WO 500-517 Operative surgical procedures. Techniques
WL Nervous system > WL 200-405 Central nervous system. Disorders. Therapeutics
WO Surgery > WO 505 Minimally invasive surgical procedures
Language:English
Series Name:Decision Support Document 83
Deposited on:15 Jul 2015 13:42
Last Modified:01 Oct 2015 12:16

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