LBI-HTA - Publications - Search - Percutaneous left atrial appendage closure for the prevention of thromboembolic events in patients with atrial fibrillation (1st Update 2014)

Reinsperger, I. and Nachtnebel, A. (2014): Percutaneous left atrial appendage closure for the prevention of thromboembolic events in patients with atrial fibrillation (1st Update 2014). Decision Support Document 44/ Update 2014.

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Abstract

The most frequently occurring complication in patients with atrial fibrillation is thromboembolism and in particular ischaemic stroke. It is believed that in more than 90% of all cases the thrombus originates from the left atrial appendage. Currently, the gold standard in the therapy of atrial fibrillation is oral anticoagulation (OAC) with vitamin-K antagonists. The percutaneous closure of the left atrial appendage is a non-pharmacological approach aiming at preventing thromboembolic events, such as ischaemic stroke. This systematic review is an update of the review compiled in 2011 and aims to assess the efficacy and safety of percutaneous left atrial appendage closure compared to OAC with vitamin K antagonists for stroke prevention in patients with atrial fibrillation.

Item Type:Decision Support Document
Keywords:Percutaneous left atrial appendage closure, oral anticoagulation, atrial fibrillation, thrombembolism, stroke
Subjects:WO Surgery > WO 500-517 Operative surgical procedures. Techniques
W Health professions > W 100-275 Medical, dental and pharmaceutical service plans
WG Cardiovascular system
Language:German
Series Name:Decision Support Document 44/ Update 2014
Deposited on:15 Jul 2014 20:15
Last Modified:16 Jul 2014 13:11

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