Breuer, J. and Nachtnebel, A. (2014): Implantation of endobronchial valves in patients with emphysema. Update 2014. Decision Support Document 20/ Update 2014.
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In this review article, endobronchial valve implantation in patients with pulmonary emphysema was evaluated for efficacy and safety. A systematic literature search was conducted, followed by a supplementary hand search. Three randomised controlled trials and eight observational studies were identified.
Due to methodological deficiencies of the randomised controlled trials and the uncontrolled study design of observational studies, the quality of the evidence was assessed according to GRADE as moderate to very low. The available evidence suggests that the investigated intervention is equally effective but less secure than drug therapy.
|Item Type:||Decision Support Document|
|Keywords:||Endobronchial valve,emphysema, COPD, bronchoscopy, lung volume reduction|
|Subjects:||WB Practice of medicine > WB 300-962 Therapeutics|
WF Respiratory system
WO Surgery > WO 505 Minimally invasive surgical procedures
WO Surgery > WO 500-517 Operative surgical procedures. Techniques
W Health professions > W 100-275 Medical, dental and pharmaceutical service plans
|Series Name:||Decision Support Document 20/ Update 2014|
|Deposited on:||15 Jul 2014 19:49|
|Last Modified:||18 Jun 2018 12:54|
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